Description

1-Bromo-3-Chloro-4-Fluoro-2-Methoxybenzene is a high-purity, multi-substituted benzene derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering precise reactivity for selective functionalization. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and anti-infective applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogen and methoxy substituents for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to construct complex aromatic systems.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-Bromo-3-Chloro-4-Fluoro-2-Methoxybenzene
CAS No.	1784628-47-2
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	2-Bromo-6-Chloro-3-Fluoroanisole; 3-Chloro-4-Fluoro-2-Methoxybromobenzene; 2-Methoxy-1-Bromo-3-Chloro-4-Fluorobenzene; 1-Bromo-3-Chloro-4-Fluoro-2-Methoxybenzene; Benzene, 1-bromo-3-chloro-4-fluoro-2-methoxy-; 3-Chloro-4-fluoro-2-methoxy-1-bromobenzene; 4-Fluoro-1-bromo-3-chloro-2-methoxybenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-4-Fluoro-2-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.