Description

6-Bromo-1-Methyl-3-(Trifluoromethyl)-1H-Indazole is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. Its unique molecular architecture, featuring both bromo and trifluoromethyl substituents on the indazole core, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for drug discovery, lead optimization, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science: Serves as a precursor for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes and enzyme inhibitors to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for client projects.

Basic Information

Product Name	6-Bromo-1-Methyl-3-(Trifluoromethyl)-1H-Indazole
CAS No.	1784437-23-5
Molecular Formula	C9H6BrF3N2
Molecular Weight	279.06 g/mol
Synonyms	6-Bromo-1-methyl-3-(trifluoromethyl)-1H-indazole; 1H-Indazole, 6-bromo-1-methyl-3-(trifluoromethyl)-; 6-Bromo-1-methyl-3-trifluoromethylindazole; 6-Bromo-1-methyl-3-(trifluoromethyl)indazole; 1784437-23-5; 6-Br-1-Me-3-CF3-1H-Indazole
EINECS	Contact for details

Quality Control

Our 6-Bromo-1-Methyl-3-(Trifluoromethyl)-1H-Indazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and impurity profiles. Our quality commitment aligns with the standards expected for pharmaceutical-grade intermediates, supporting our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.