Description

8-Chloroisoquinolin-4-Amine is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the isoquinoline scaffold.
• Ligand Synthesis: Acts as a starting material for creating novel chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic semiconductors, conductive polymers, and advanced organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Utilized to build molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences sector.

Basic Information

Product Name	8-Chloroisoquinolin-4-Amine
CAS No.	1784285-89-7
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	4-Amino-8-chloroisoquinoline; 8-Chloro-4-isoquinolinamine; 8-Chloro-isoquinolin-4-ylamine; 8-Chloro-4-amino-isoquinoline; 4-Isoquinolinamine, 8-chloro-; 8-Chloro-4-isoquinolamine; 1784285-89-7; 8-Cl-IQ-4-NH2
EINECS	Contact for details

Quality Control

Every batch of 8-Chloroisoquinolin-4-Amine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) including HPLC purity, NMR, and mass spectrometry confirmation is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.