Description

5-Bromo-1-Methyl-3-(Trifluoromethyl)-1H-Indazole is a high-value, multi-functional heterocyclic building block characterized by its bromo and trifluoromethyl substituents. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly due to the favorable properties imparted by the trifluoromethyl group. It serves as a critical intermediate for pharmaceutical, agrochemical, and advanced material scientists seeking to incorporate complex indazole scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the indazole core contributes to biological activity.
• Material Science Research: Serves as a building block for organic electronic materials, ligands for catalysis, and specialty polymers.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical synthesis services targeting complex, fluorinated heterocycles.

Basic Information

Product Name	5-Bromo-1-Methyl-3-(Trifluoromethyl)-1H-Indazole
CAS No.	1784018-72-9
Molecular Formula	C9H6BrF3N2
Molecular Weight	279.06 g/mol
Synonyms	5-Bromo-1-methyl-3-(trifluoromethyl)-1H-indazole; 1H-Indazole, 5-bromo-1-methyl-3-(trifluoromethyl)-; 1784018-72-9; 5-Bromo-1-methyl-3-trifluoromethylindazole; 3-Trifluoromethyl-5-bromo-1-methylindazole
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Methyl-3-(Trifluoromethyl)-1H-Indazole is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and MS confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.