Description

2-(3-Bromo-5-Fluoro-Phenyl)-Propan-2-Ol is a high-purity, halogenated aromatic alcohol building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on the phenyl ring, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a crucial building block for developing novel herbicides, fungicides, and insecticides, where the bromo-fluoro-phenyl moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of halogen handles.
• Material Science Research: Employed in the synthesis of monomers and functionalized polymers for advanced materials with specific optical or electronic properties.
• Chemical Biology Probes: Acts as a starting point for synthesizing molecular probes and tags used in biochemical assay development and diagnostic research.

Basic Information

Product Name	2-(3-Bromo-5-Fluoro-Phenyl)-Propan-2-Ol
CAS No.	1783974-49-1
Molecular Formula	C9H10BrFO
Molecular Weight	233.08 g/mol
Synonyms	2-(3-Bromo-5-fluorophenyl)propan-2-ol; 1-(3-Bromo-5-fluorophenyl)-2-methylpropan-2-ol; 3-Bromo-5-fluoro-α,α-dimethylbenzyl alcohol; 2-Propanol, 2-(3-bromo-5-fluorophenyl)-; 3'-Bromo-5'-fluoro-2-methylpropiophenone hydrate (related precursor); 2-Methyl-2-(3-bromo-5-fluorophenyl)propan-1-ol (isomer)
EINECS	Contact for details

Quality Control

Our 2-(3-Bromo-5-Fluoro-Phenyl)-Propan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.