Description

7-Fluoro-1H-Indazole-4-Carboxylic Acid is a high-value fluorinated indazole derivative, serving as a critical building block in modern organic synthesis. Its molecular structure, featuring both a carboxylic acid and a fluorine-substituted indazole core, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially kinase inhibitors and anti-cancer agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile functional groups.
• Agrochemical Synthesis: Serves as a precursor for developing advanced, fluorinated active ingredients with enhanced biological activity and stability.
• Material Science: Potential building block for advanced organic materials and ligands in catalytic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	7-Fluoro-1H-Indazole-4-Carboxylic Acid
CAS No.	1783619-00-0
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	7-Fluoro-1H-indazole-4-carboxylic acid; 4-Carboxy-7-fluoro-1H-indazole; 7-Fluoro-4-indazolecarboxylic acid; 1H-Indazole-4-carboxylic acid, 7-fluoro-; 1783619-00-0; 7-Fluoroindazole-4-carboxylic acid; 4-Carboxy-7-fluoroindazole
EINECS	Contact for details

Quality Control

Our 7-Fluoro-1H-Indazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.