Description

4-Bromo-6-(Trifluoromethyl)Isoquinoline is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is particularly significant for its unique molecular architecture, combining a bromo-substituent for cross-coupling reactions with a trifluoromethyl group to impart desirable physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials. Our supply ensures consistent quality and reliable availability for critical global development pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the biological activity of the isoquinoline core.
• Material Science Research: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient character.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis and organocatalysis.
• Fluorine Chemistry Studies: An important reagent for investigating structure-activity relationships (SAR) influenced by the trifluoromethyl group.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex molecules for client projects.

Basic Information

Item	Detail
Product Name	4-Bromo-6-(Trifluoromethyl)Isoquinoline
CAS No.	1782509-09-4
Molecular Formula	C₁₀H₅BrF₃N
Molecular Weight	276.06 g/mol
Synonyms	4-Bromo-6-(trifluoromethyl)isoquinoline; 6-(Trifluoromethyl)-4-bromoisoquinoline; 4-Bromo-6-trifluoromethylisoquinoline; Isoquinoline, 4-bromo-6-(trifluoromethyl)-; 1782509-09-4
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-6-(Trifluoromethyl)Isoquinoline is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and GC-MS, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.