Description

Benzo[B]Thiophene, 3-Bromo-5-Fluoro-4-Methyl- is a high-purity, multi-functional heterocyclic building block designed for advanced organic synthesis. This compound is valued for its precise molecular architecture, which enables the introduction of halogenated thiophene motifs into complex target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a core structure for synthesizing novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the synthesis of organic semiconductors, conductive polymers, and advanced electronic materials due to the electron-rich thiophene core.
• Chemical Synthesis: Functions as a versatile building block for Suzuki, Stille, and other cross-coupling reactions to construct complex polycyclic aromatic systems.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	Benzo[B]Thiophene, 3-Bromo-5-Fluoro-4-Methyl-
CAS No.	1781825-71-5
Molecular Formula	C9H6BrFS
Molecular Weight	245.11 g/mol
Synonyms	3-Bromo-5-fluoro-4-methylbenzo[b]thiophene; 4-Methyl-3-bromo-5-fluorobenzo[b]thiophene; 5-Fluoro-3-bromo-4-methylbenzo[b]thiophene; Benzo[b]thiophene, 3-bromo-5-fluoro-4-methyl-; 3-Bromo-5-fluoro-4-methyl-1-benzothiophene
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene, 3-Bromo-5-Fluoro-4-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, GC-MS, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.