Description

7-Bromo-6-Fluorobenzo[B]Thiophene-2-Carboxylic Acid CAS NO 1781503-02-3 is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates halogenated benzo[b]thiophene and carboxylic acid functionalities, enabling precise structural modifications. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, enzyme modulators, and other small-molecule therapeutics.
• Agrochemical Research: Serves as a versatile scaffold for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated benzo[b]thiophene core.
• Material Science: Used in the research and development of organic electronic materials, such as organic semiconductors and light-emitting materials, due to its conjugated system.
• Chemical Synthesis: Acts as a crucial building block for constructing more complex heterocyclic compounds and for introducing specific functional groups via its reactive carboxylic acid and halogen sites.
• Ligand & Catalyst Development: Employed in the design of novel ligands for metal-catalyzed reactions and organocatalysts.

Basic Information

Product Name	7-Bromo-6-Fluorobenzo[B]Thiophene-2-Carboxylic Acid
CAS No.	1781503-02-3
Molecular Formula	C9H4BrFO2S
Molecular Weight	275.10 g/mol
Synonyms	7-Bromo-6-fluorobenzo[b]thiophene-2-carboxylic acid; 2-Benzo[b]thiophenecarboxylic acid, 7-bromo-6-fluoro-; 7-Bromo-6-fluoro-1-benzothiophene-2-carboxylic acid; 7-Bromo-6-fluorobenzothiophene-2-carboxylic acid; 1781503-02-3; 7-Br-6-F-BT-2-COOH; 6-Fluoro-7-bromobenzo[b]thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Bromo-6-Fluorobenzo[B]Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.