Description

1H-Indazole, 5-Bromo-1-Methyl-3-(1-Methylethyl)- CAS NO 1781342-16-2 is a high-purity, functionalized indazole derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which is engineered for the development of novel compounds with targeted biological or material properties. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, anti-cancer agents, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for advanced organic materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology: Employed as a molecular probe or a tag in the study of biological pathways and protein interactions.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and custom synthesis houses developing proprietary compounds for clients.
• Academic Research: Used in universities and research institutes for methodological studies in heterocyclic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1H-Indazole, 5-Bromo-1-Methyl-3-(1-Methylethyl)-
CAS No.	1781342-16-2
Molecular Formula	C11H13BrN2
Molecular Weight	253.14 g/mol
Synonyms	5-Bromo-1-methyl-3-(propan-2-yl)-1H-indazole; 5-Bromo-1-methyl-3-isopropyl-1H-indazole; 3-Isopropyl-5-bromo-1-methyl-1H-indazole; 1-Methyl-5-bromo-3-isopropylindazole; 5-Bromo-3-isopropyl-1-methylindazole; 1H-Indazole, 5-bromo-1-methyl-3-(1-methylethyl)-; 1781342-16-2
EINECS	Contact for details

Quality Control

Our 1H-Indazole, 5-Bromo-1-Methyl-3-(1-Methylethyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.