Description

6-Bromo-5-Methyl-1,2,3,4-Tetrahydro-Isoquinoline is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is critical for medicinal chemistry research and the synthesis of complex bioactive molecules, offering a strategic point for further functionalization. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds and developing new synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel active ingredients for crop protection products.
• Ligand and Catalyst Development: Employed as a building block for creating novel chiral ligands, organocatalysts, or metal-organic complexes.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, dyes, and other high-value organic compounds.
• Academic Research: Used in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-5-Methyl-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	1780904-96-2
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	6-Bromo-5-methyl-1,2,3,4-tetrahydroisoquinoline; 5-Methyl-6-bromo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6-bromo-5-methylisoquinoline; 6-Bromo-5-methyl-THIQ; 1780904-96-2; 6-Br-5-Me-THIQ
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Methyl-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.