Description

7-Bromo-1-Oxo-1,2-Dihydroisoquinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct brominated isoquinoline carboxylic acid structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small molecule drug candidates, particularly for oncology and CNS targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its reactive bromine and carboxylic acid functional groups.
• API Synthesis: Serves as a precursor in multi-step synthetic routes for complex active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Product Name	7-Bromo-1-Oxo-1,2-Dihydroisoquinoline-4-Carboxylic Acid
CAS No.	1780191-92-5
Molecular Formula	C10H6BrNO3
Molecular Weight	268.07 g/mol
Synonyms	7-Bromo-1,2-dihydro-1-oxo-4-isoquinolinecarboxylic acid; 7-Bromo-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid; 4-Carboxy-7-bromo-1,2-dihydroisoquinolin-1-one; 7-Bromo-1-oxo-1,2-dihydro-4-isoquinolinecarboxylic acid; 1780191-92-5; 7-Bromo-1-oxo-1,2-dihydroisoquinoline-4-carboxylate
EINECS	Contact for details

Quality Control

Our 7-Bromo-1-Oxo-1,2-Dihydroisoquinoline-4-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.