Description

2-(4-Bromophenyl)-2,2-Difluoro-Ethanol is a high-value fluorinated organic building block characterized by its bromophenyl and difluoroethanol functional groups. This compound is essential for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where the introduction of fluorine atoms is critical for modulating biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro moiety enhances efficacy and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromophenyl group makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and the properties of fluorinated compounds.
• Polymer Modification: Used to introduce fluorine-containing side chains into polymers to alter surface properties, such as hydrophobicity and chemical resistance.

Basic Information

Product Name	2-(4-Bromophenyl)-2,2-Difluoro-Ethanol
CAS No.	1779939-06-8
Molecular Formula	C8H7BrF2O
Molecular Weight	237.04 g/mol
Synonyms	2-(4-Bromophenyl)-2,2-difluoroethanol; 1-(4-Bromophenyl)-2,2-difluoroethan-1-ol; 4-Bromo-α,α-difluorobenzeneethanol; (4-Bromophenyl)difluoromethyl carbinol; 2,2-Difluoro-2-(4-bromophenyl)ethanol; α,α-Difluoro-4-bromobenzeneethanol; 1-(4-Bromophenyl)-2,2-difluoro-1-ethanol
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-2,2-Difluoro-Ethanol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container must be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.