Description

1-(2-Cyanoethyl)-1H-Pyrazole-4-Boronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. Its primary value lies in its dual functionality, serving as a versatile intermediate in cross-coupling reactions, most notably the Suzuki-Miyaura reaction, which is fundamental to constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a monomer or precursor in the development of advanced polymers and organic electronic materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic pathways and catalytic processes.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Bioconjugation: Potential use in the development of bioconjugates and probes for diagnostic applications.

Basic Information

Product Name	1-(2-Cyanoethyl)-1H-Pyrazole-4-Boronic Acid
CAS No.	1778667-08-5
Molecular Formula	C6H8BN3O2
Molecular Weight	164.96 g/mol
Synonyms	1H-Pyrazole-4-boronic acid, 1-(2-cyanoethyl)-; 1-(2-Cyanoethyl)-1H-pyrazole-4-boronic acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-cyanoethyl)-1H-pyrazole; 1-(2-Cyanoethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; Pyrazole-4-boronic acid, 1-(2-cyanoethyl)-1H-; 1-(Cyanoethyl)pyrazole-4-boronic acid; B-[1-(2-Cyanoethyl)-1H-pyrazol-4-yl]boronic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Cyanoethyl)-1H-Pyrazole-4-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.