Description

4-Bromo-5-Fluoro-1H-Indazol-3-Amine is a high-purity, functionalized indazole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated structure, which provides reactive handles for further chemical modifications, enabling the development of novel molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of targeted small molecule libraries and potential drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially in kinase inhibitor programs.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization studies to explore structure-activity relationships (SAR).
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Agrochemical Synthesis: Employed in the discovery of novel herbicides and pesticides due to its heterocyclic core.
• Material Science: Potential precursor for the synthesis of specialized organic electronic materials and ligands for catalysis.

Basic Information

Product Name	4-Bromo-5-Fluoro-1H-Indazol-3-Amine
CAS No.	1715912-67-6
Molecular Formula	C7H5BrFN3
Molecular Weight	230.04 g/mol
Synonyms	4-Bromo-5-fluoro-1H-indazol-3-amine; 3-Amino-4-bromo-5-fluoro-1H-indazole; 4-Bromo-5-fluoro-1H-indazol-3-ylamine; 1715912-67-6; 4-Bromo-5-fluoroindazol-3-amine; 5-Fluoro-4-bromo-1H-indazol-3-amine
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Fluoro-1H-Indazol-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.