Description

(R)-Isopropyl 2-(((S)-(Perfluorophenoxy)(Phenoxy)Phosphoryl)Amino)Propanoate is a high-purity, chiral organophosphorus compound of significant interest in advanced synthetic chemistry. Its value lies in its role as a sophisticated building block or chiral auxiliary for the synthesis of complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control in their synthetic pathways.

Application

• As a key chiral intermediate or building block in the synthesis of novel active pharmaceutical ingredients (APIs).
• Utilized in asymmetric synthesis and catalysis research to induce or control stereoselectivity.
• Potential use in the development of agrochemicals, such as herbicides or insecticides with specific activity profiles.
• Application in material science for creating specialty polymers or ligands with unique properties.
• Serving as a reference standard or analytical reagent in quality control and method development laboratories.
• Research applications in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	(R)-Isopropyl 2-(((S)-(Perfluorophenoxy)(Phenoxy)Phosphoryl)Amino)Propanoate
CAS No.	1714114-25-6
Molecular Formula	C18H17F5NO4P
Molecular Weight	437.30 g/mol
Synonyms	(R)-Isopropyl 2-(((S)-(Perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate; (S)-(Perfluorophenoxy)(phenoxy)phosphoryl-L-alanine isopropyl ester; Isopropyl (2R)-2-({[(S)-(perfluorophenoxy)(phenoxy)phosphoryl]amino})propanoate; PNP-L-Ala-OiPr (derivative); Chiral phosphoramidate isopropyl ester; (Perfluorophenyl) phenyl phosphoramidate of D-alanine isopropyl ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of (R)-Isopropyl 2-(((S)-(Perfluorophenoxy)(Phenoxy)Phosphoryl)Amino)Propanoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.