Description

6-Bromo-4-Methyl-1,2,3,4-Tetrahydroisoquinoline is a versatile brominated tetrahydroisoquinoline derivative, a privileged scaffold in medicinal chemistry. This compound matters as a high-value pharmaceutical intermediate and key building block for the synthesis of complex bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel compounds with potential therapeutic or biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to the reactive bromine atom for further functionalization.
• Agrochemical Synthesis: Employed in the development of novel pesticides and herbicides, leveraging the tetrahydroisoquinoline core's bioactivity.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, dyes, and advanced materials.
• Academic & Institutional R&D: A valuable reagent for exploratory research in organic synthesis and chemical biology at universities and research institutes.

Basic Information

Product Name	6-Bromo-4-Methyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	1710696-27-7
Molecular Formula	C₁₀H₁₂BrN
Molecular Weight	226.11 g/mol
Synonyms	6-Bromo-4-methyl-1,2,3,4-tetrahydroisoquinoline; 4-Methyl-6-bromo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6-bromo-4-methylisoquinoline; 6-Bromo-4-methyl-THIQ; 1710696-27-7
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Methyl-1,2,3,4-Tetrahydroisoquinoline is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.