Description

2-2-Ethyl-6-Fluoro-1H-Benzo[D]Imidazol-1-Ylacetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzimidazole core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and proprietary drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel benzimidazole-based active pharmaceutical ingredients (APIs).
• Drug Discovery & Medicinal Chemistry: Serves as a crucial scaffold in high-throughput screening and structure-activity relationship (SAR) studies for new drug candidates.
• Contract Research & Development (CRO/CDMO): Used by research organizations for custom synthesis and process development projects.
• Biochemical Research: Employed as a reference standard or reagent in biochemical assays and pharmacological studies.
• Preclinical Development: Integral in producing batches of lead compounds for toxicology and pharmacokinetic studies.

Basic Information

Product Name	2-2-Ethyl-6-Fluoro-1H-Benzo[D]Imidazol-1-Ylacetic Acid
CAS No.	1707367-57-4
Molecular Formula	C11H11FN2O2
Molecular Weight	222.22 g/mol
Synonyms	2-(2-Ethyl-6-fluoro-1H-benzimidazol-1-yl)acetic acid; 2-(2-Ethyl-6-fluoro-1H-benzo[d]imidazol-1-yl)acetic acid; 1H-Benzo[d]imidazole-1-acetic acid, 2-ethyl-6-fluoro-; 2-Ethyl-6-fluoro-1H-benzimidazole-1-acetic acid; 6-Fluoro-2-ethyl-1H-benzimidazole-1-acetic acid; CAS 1707367-57-4; Benzimidazole acetic acid derivative
EINECS	Contact for details

Quality Control

Our production of 2-2-Ethyl-6-Fluoro-1H-Benzo[D]Imidazol-1-Ylacetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and traceability. All material is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged exposure to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.