Description

6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzo[D]Imidazole Hydrochloride is a high-value, organoboron building block essential for modern pharmaceutical and agrochemical research. This compound, supplied as a hydrochloride salt, is prized for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone of medicinal chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and advanced materials sectors to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology, antiviral, and CNS drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a precursor for creating functionalized polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and bioconjugates for target identification and validation.
• Process Chemistry: Utilized in route scouting and optimization for the scalable manufacturing of complex organic molecules.

Basic Information

Item	Details
Product Name	6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzo[D]Imidazole Hydrochloride
CAS No.	1704081-85-5
Molecular Formula	C15H20BN2O2 · HCl
Molecular Weight	308.61 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole hydrochloride; 1H-Benzimidazole, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, hydrochloride (1:1); 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole HCl; Benzimidazole-6-boronic acid pinacol ester hydrochloride; 6-Borono-1H-benzimidazole pinacol ester hydrochloride
EINECS	Contact for details

Quality Control

Our 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzo[D]Imidazole Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.