Description

6‐Bromo‐5‐Chloro‐2,3‐Dihydro‐1H‐Indol‐2‐One is a high-purity, multi-halogenated indolinone derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for constructing complex molecules with tailored biological and material properties. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated indole core.
• Material Science Research: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and contract research organizations (CROs) requiring specific halogenated heterocycles.
• Academic & Industrial R&D: Utilized in exploratory chemistry for developing new synthetic methodologies and discovering compounds with novel properties.

Basic Information

Product Name	6‐Bromo‐5‐Chloro‐2,3‐Dihydro‐1H‐Indol‐2‐One
CAS No.	1699598-91-8
Molecular Formula	C8H5BrClNO
Molecular Weight	246.49 g/mol
Synonyms	5-Chloro-6-bromo-2-indolinone; 6-Bromo-5-chloro-2-indolinone; 6-Bromo-5-chloro-1,3-dihydro-2H-indol-2-one; 6-Bromo-5-chlorooxindole; 2H-Indol-2-one, 6-bromo-5-chloro-1,3-dihydro-; 1699598-91-8; 5-Chloro-6-bromooxindole
EINECS	Contact for details

Quality Control

Our 6‐Bromo‐5‐Chloro‐2,3‐Dihydro‐1H‐Indol‐2‐One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.