Description

1H-Indole-2-Carboxylic Acid, 4,6,7-Trifluoro- is a high-value, multi-fluorinated indole derivative serving as a critical building block in advanced organic synthesis. Its unique trifluorinated structure provides enhanced metabolic stability and lipophilicity, making it indispensable for the development of novel bioactive molecules. This compound is primarily sought by pharmaceutical and agrochemical R&D teams for the creation of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used to develop new herbicides and fungicides, where the fluorine atoms improve compound uptake and environmental stability.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag to study protein interactions and enzyme mechanisms due to its distinctive spectroscopic signature.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and medicinal chemistry programs in university and CRO laboratories.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 4,6,7-Trifluoro-
CAS No.	1699249-56-3
Molecular Formula	C9H4F3NO2
Molecular Weight	215.13 g/mol
Synonyms	4,6,7-Trifluoro-1H-indole-2-carboxylic acid; 4,6,7-Trifluoroindole-2-carboxylic acid; 2-Carboxy-4,6,7-trifluoroindole; 1H-Indole-2-carboxylic acid, 4,6,7-trifluoro-; 4,6,7-Trifluoro-2-indolecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-2-Carboxylic Acid, 4,6,7-Trifluoro- adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; ensure it is stored separately from such materials to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.