Description

3-Iodo-1H-Indole-6-Carbonitrile is a halogenated indole derivative that serves as a versatile and high-value synthetic building block. This compound is critical for medicinal chemistry research and the development of novel pharmaceutical agents, particularly in kinase inhibitor and oncology drug discovery programs. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted small molecule drugs, especially kinase inhibitors for oncology.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds or probes to study biological pathways.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel crop protection agents.
• Material Science: Building block for advanced organic electronic materials and functional polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	3-Iodo-1H-Indole-6-Carbonitrile
CAS No.	1696315-42-0
Molecular Formula	C9H5IN2
Molecular Weight	268.06 g/mol
Synonyms	6-Cyano-3-iodo-1H-indole; 3-Iodo-6-cyanoindole; 1H-Indole-6-carbonitrile, 3-iodo-; 3-Iodoindole-6-carbonitrile; 3-Iodo-1H-indole-6-carbonitrile; 1696315-42-0
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-1H-Indole-6-Carbonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.