Description

1-Bromo-2-Fluoro-5-Iodo-4-Methoxy-Benzene is a high-purity, multi-halogenated benzene derivative designed for advanced synthetic chemistry. This compound serves as a versatile and critical building block in the development of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is essential for chemists and R&D teams in the life sciences, material science, and specialty chemical sectors who require reliable, high-quality intermediates for coupling reactions and structure-activity relationship studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system and oncological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced polymers and liquid crystals with specific electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of bromo and iodo substituents.
• Chemical Synthesis: Employed in medicinal chemistry for lead optimization and the construction of complex, halogen-diverse molecular libraries.
• Diagnostic Reagents: Potential use in the synthesis of radiolabeled compounds or fluorescent probes for imaging and diagnostic applications.

Basic Information

Product Name	1-Bromo-2-Fluoro-5-Iodo-4-Methoxy-Benzene
CAS No.	1692438-02-0
Molecular Formula	C7H5BrFIO
Molecular Weight	330.92 g/mol
Synonyms	4-Bromo-5-Fluoro-2-Iodoanisole; 2-Bromo-1-Fluoro-4-Iodo-5-Methoxybenzene; Benzene, 1-bromo-2-fluoro-5-iodo-4-methoxy-; 5-Bromo-4-fluoro-2-iodoanisole; 1-Bromo-2-fluoro-5-iodo-4-methoxybenzene; 4-Methoxy-2-bromo-1-fluoro-5-iodobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Fluoro-5-Iodo-4-Methoxy-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.