Description

3-Chloro-5-Methoxyisoquinoline is a versatile and high-value heterocyclic building block, essential for advanced organic synthesis and pharmaceutical research. Its unique molecular structure, featuring both chloro and methoxy substituents on the isoquinoline core, makes it a critical intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and anti-infective compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, ligands for catalysis, and advanced polymers due to its electron-rich aromatic system.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tag in the design of chemical probes for studying biological pathways and protein function.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic routes in academic and industrial R&D laboratories.

Basic Information

Product Name	3-Chloro-5-Methoxyisoquinoline
CAS No.	1691715-12-4
Molecular Formula	C₁₀H₈ClNO
Molecular Weight	193.63 g/mol
Synonyms	5-Methoxy-3-chloroisoquinoline; 3-Chloro-5-methoxy-isoquinoline; Isoquinoline, 3-chloro-5-methoxy-; 1691715-12-4
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-Methoxyisoquinoline is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for assay, purity (by HPLC), and identification (by IR and NMR).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.