Description

Isoquinoline, 5-Bromo-1-Chloro-8-Methoxy- CAS NO 1690846-94-6 is a high-purity, multi-substituted isoquinoline derivative, a crucial advanced intermediate in modern synthetic chemistry. Its complex halogenated and methoxylated structure makes it an invaluable building block for constructing sophisticated molecular architectures with targeted properties. This compound is primarily sought after by research institutions and pharmaceutical developers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders, cancer, and infectious diseases.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and pesticides with novel modes of action.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the design of molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Catalyst & Ligand Development: The isoquinoline core can be further functionalized to create novel ligands for asymmetric catalysis and transition metal complexes.
• Academic & Contract Research: Essential for fundamental organic chemistry research and method development in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Isoquinoline, 5-Bromo-1-Chloro-8-Methoxy-
CAS No.	1690846-94-6
Molecular Formula	C₁₀H₇BrClNO
Molecular Weight	272.52 g/mol
Synonyms	5-Bromo-1-chloro-8-methoxyisoquinoline; 1-Chloro-5-bromo-8-methoxyisoquinoline; 8-Methoxy-5-bromo-1-chloroisoquinoline; 5-Bromo-8-methoxy-1-chloroisoquinoline; Isoquinoline, 1-chloro-5-bromo-8-methoxy-; 1690846-94-6
EINECS	Contact for details

Quality Control

Our Isoquinoline, 5-Bromo-1-Chloro-8-Methoxy- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP and ISO guidelines ensures the material meets the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.