Description

3-Thiophenebutanoic Acid, α-Amino-, (αs)- is a high-purity, non-natural amino acid derivative featuring a thiophene moiety, serving as a critical chiral building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and sophisticated agrochemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-fidelity, structurally complex intermediates for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide mimetics, enzyme inhibitors, and novel drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that incorporate heterocyclic scaffolds for enhanced activity.
• Ligand & Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Potential building block for functionalized polymers and advanced organic materials with specific electronic or photophysical properties.
• Bioconjugation & Probe Synthesis: Utilized in medicinal chemistry for labeling studies and the creation of biochemical probes due to its reactive amino and carboxylic acid functional groups.

Basic Information

Product Name	3-Thiophenebutanoic Acid, α-Amino-, (αs)-
CAS No.	1689953-13-6
Molecular Formula	C8H11NO2S
Molecular Weight	185.24 g/mol
Synonyms	(αS)-α-Amino-3-thiophenebutanoic acid; (S)-2-Amino-4-(thiophen-3-yl)butanoic acid; 4-(3-Thienyl)-L-homoalanine; L-4-(3-Thienyl)homoalanine; 3-Thiophene-L-homoalanine; (S)-4-(Thiophen-3-yl)-2-aminobutanoic acid; Non-natural amino acid thiophene derivative; Chiral thiophene amino acid
EINECS	Contact for details

Quality Control

Our 3-Thiophenebutanoic Acid, α-Amino-, (αs)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (by HPLC/NMR), enantiomeric excess, and related substances is provided with every shipment to guarantee reproducible results and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.