Description

4-Fluoro-7-Mercapto-2,3-Dihydro-1H-Inden-1-One is a high-value, multi-functional heterocyclic building block featuring both a fluorine substituent and a reactive thiol (mercapto) group. This unique molecular architecture makes it a critical intermediate for the synthesis of advanced pharmaceutical compounds and specialty materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active agent research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for organic electronic materials, ligands for catalysis, and functional polymers.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.
• Ligand Synthesis: The thiol group allows for the preparation of chelating ligands used in metal-organic frameworks (MOFs) and homogeneous catalysis.

Basic Information

Product Name	4-Fluoro-7-Mercapto-2,3-Dihydro-1H-Inden-1-One
CAS No.	1672661-79-8
Molecular Formula	C9H7FOS
Molecular Weight	182.22 g/mol
Synonyms	4-Fluoro-7-mercaptoindan-1-one; 1H-Inden-1-one, 4-fluoro-2,3-dihydro-7-mercapto-; 7-Mercapto-4-fluoro-2,3-dihydro-1H-inden-1-one; 4-Fluoro-7-sulfanyl-2,3-dihydro-1H-inden-1-one; FMI (abbreviation); 4-F-7-MI
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-7-Mercapto-2,3-Dihydro-1H-Inden-1-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive and easily oxidized; avoid exposure to air, moisture, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.