Description

1H-Indole-1-Carboxylic Acid, 4-(Hydroxymethyl)-5-Methoxy-7-Methyl-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex indole-based molecular structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and fine chemical production.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Organic Synthesis Reagent: Used in research-scale and process chemistry for constructing complex indole derivatives and heterocyclic compounds.
• Agrochemical Research: Serves as a precursor in the development of new-generation pesticides and plant growth regulators.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced organic materials.
• Academic & Contract Research: Essential for medicinal chemistry programs and custom synthesis projects in university and CRO (Contract Research Organization) laboratories.

Basic Information

Item	Detail
Product Name	1H-Indole-1-Carboxylic Acid, 4-(Hydroxymethyl)-5-Methoxy-7-Methyl-, 1,1-Dimethylethyl Ester
CAS No.	1644667-10-6
Molecular Formula	C17H21NO5
Molecular Weight	319.35 g/mol
Synonyms	tert-Butyl 4-(hydroxymethyl)-5-methoxy-7-methyl-1H-indole-1-carboxylate; 4-(Hydroxymethyl)-5-methoxy-7-methyl-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)-5-methoxy-7-methylindole; Boc-4-(hydroxymethyl)-5-methoxy-7-methylindole; 7-Methyl-5-methoxy-4-hydroxymethylindole-1-carboxylic acid tert-butyl ester; Indole-1-carboxylic acid, 4-(hydroxymethyl)-5-methoxy-7-methyl-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-1-Carboxylic Acid, 4-(Hydroxymethyl)-5-Methoxy-7-Methyl-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.