Description

1,2-Dibromobenzene-3,4,5,6-D4 CAS NO 1643577-34-7 is a deuterium-labeled isotopologue of 1,2-dibromobenzene, where four hydrogen atoms are replaced with deuterium, serving as a critical internal standard and tracer in advanced analytical chemistry. This high-purity labeled compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry and NMR spectroscopy by correcting for matrix effects and instrument variability. It is primarily needed by research scientists and quality control laboratories in the pharmaceutical, agrochemical, and environmental analysis sectors for method development, metabolic studies, and precise quantification.

Application

• Internal Standard for GC-MS/LC-MS: Used as a stable, non-interfering reference compound for the accurate quantification of 1,2-dibromobenzene and related aromatics in complex matrices.
• NMR Spectroscopy Solvent & Tracer: Employed in mechanistic and metabolic studies to track reaction pathways and molecular interactions without signal interference from protons.
• Pharmaceutical Research: Facilitates drug metabolism and pharmacokinetics (DMPK) studies by acting as a deuterated tracer for metabolite identification and quantification.
• Environmental Analysis: Critical for the precise monitoring and analysis of brominated aromatic pollutants in soil, water, and air samples.
• Chemical Synthesis Intermediate: Serves as a specialized building block in the synthesis of more complex deuterated compounds for research purposes.
• Quality Assurance & Method Validation: Provides a certified reference material for validating analytical methods and ensuring regulatory compliance in testing laboratories.

Basic Information

Product Name	1,2-Dibromobenzene-3,4,5,6-D4
CAS No.	1643577-34-7
Molecular Formula	C6D4Br2
Molecular Weight	239.90 g/mol
Synonyms	1,2-Dibromobenzene-d4; Benzene-d4, 1,2-dibromo-; o-Dibromobenzene-d4; 3,4,5,6-Tetradeutero-1,2-dibromobenzene; Deuterated 1,2-Dibromobenzene; [2H4]-1,2-Dibromobenzene; 1,2-Dibromo-3,4,5,6-tetradeuterobenzene; Perdeuterated 1,2-Dibromobenzene (partial)
EINECS	Contact for details

Quality Control

Our 1,2-Dibromobenzene-3,4,5,6-D4 is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analysis, including NMR and Mass Spectrometry, to confirm chemical and isotopic identity, purity, and absence of protiated impurities. Certificates of Analysis (COA) detailing all specifications are available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.