Description

3-Bromo-5-Trifluoromethylpyridine-D3 is a high-purity, deuterium-labeled isotopologue of a key pyridine-based building block. This compound is specifically designed for advanced research and development, offering a stable isotopic label for precise analytical and metabolic studies. It is an essential intermediate for pharmaceutical chemists and agrochemical researchers developing novel active ingredients, particularly in the creation of deuterated drug candidates and sophisticated tracer molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of deuterated active pharmaceutical ingredients (APIs) in drug discovery and development.
• Metabolic Tracer: Used in mass spectrometry and NMR-based studies to track metabolic pathways and drug metabolism (pharmacokinetics/pharmacodynamics).
• Agrochemical Research: Serves as a precursor in the development of novel, labeled herbicides, fungicides, and insecticides.
• Material Science: Employed in the synthesis of advanced organic electronic materials and liquid crystals where isotopic purity can influence properties.
• Analytical Reference Standard: Acts as an internal standard for quantitative analysis via LC-MS or GC-MS, ensuring high accuracy in complex matrices.

Basic Information

Product Name	3-Bromo-5-Trifluoromethylpyridine-D3
CAS No.	1643577-15-4
Molecular Formula	C7H2D3BrF3N
Molecular Weight	230.02 g/mol (approx.)
Synonyms	3-Bromo-5-(trifluoromethyl)pyridine-2,4,6-d3; 2,4,6-Trideutero-3-bromo-5-(trifluoromethyl)pyridine; 3-Bromo-5-trifluoromethylpyridine-d3; Deutero-labeled 3-Bromo-5-Trifluoromethylpyridine; Pyridine-d3, 3-bromo-5-(trifluoromethyl)-; Bromo(trifluoromethyl)pyridine-D3
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Trifluoromethylpyridine-D3 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR (¹H, ¹³C, ¹⁹F) for structural confirmation and deuterium incorporation, and HPLC for chemical purity assessment. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep the container sealed under an inert atmosphere to maintain purity and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Incorporation)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.