Description

Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, 2,6-Dibromo-N,n-Bis[(1S)-1-Phenylethyl]-, (11Br)- is a sophisticated chiral organophosphorus compound, distinguished by its complex dinaphthodioxaphosphepin core and brominated, stereodefined substituents. This compound is of significant value as a highly specialized ligand or catalyst precursor in advanced synthetic chemistry, enabling precise stereocontrol in challenging transformations. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex, optically active molecules.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or precursor for transition metal catalysts in enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: A key building block or directing agent in the multi-step synthesis of active pharmaceutical ingredients (APIs) requiring high enantiopurity.
• Advanced Material Research: Potential use in the development of chiral functional materials or as a component in molecular recognition systems.
• Methodology Development: Employed by academic and industrial research groups to develop new catalytic protocols and synthetic methodologies.
• Ligand Library Construction: A valuable member of diverse ligand libraries used for high-throughput screening in catalyst discovery.

Basic Information

Product Name	Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, 2,6-Dibromo-N,n-Bis[(1S)-1-Phenylethyl]-, (11Br)-
CAS No.	1642864-91-2
Molecular Formula	C34H27Br2NO2P
Molecular Weight	681.37 g/mol
Synonyms	(11Br)-2,6-Dibromo-N,N-bis[(1S)-1-phenylethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; (S,S)-2,6-Dibromo-4-((S)-1-phenylethylamino)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine; Chiral Brominated Dioxaphosphepin Ligand; CAS 1642864-91-2
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing specific results for chiral purity (ee), chemical purity, and other critical parameters are available upon request. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.