Description

Benzamide, 2-[(1-Acetyl-3-Iodo-1H-Indazol-6-Yl)Thio]-n-Methyl- is a high-purity, synthetic organic compound featuring a benzamide core linked to a substituted indazole moiety via a thioether bridge. This structurally complex molecule is of significant interest for its potential as a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly in oncology and targeted drug discovery.

Application

This specialized chemical serves as a critical building block in several high-value research and industrial applications:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, especially those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes for new therapeutic agents.
• Oncology Drug Discovery: Investigated for the development of potential kinase inhibitors and other targeted cancer therapies due to its indazole-based structure.
• Biochemical Tool Compound: Serves as a probe or reference standard in biochemical assays to study protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for clinical trials.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and organic synthesis methodologies.

Basic Information

Product Name	Benzamide, 2-[(1-Acetyl-3-Iodo-1H-Indazol-6-Yl)Thio]-n-Methyl-
CAS No.	1639138-00-3
Molecular Formula	C17H14IN3O2S
Molecular Weight	451.28 g/mol
Synonyms	N-Methyl-2-[[1-acetyl-3-iodo-1H-indazol-6-yl]thio]benzamide; 2-[(1-Acetyl-3-iodo-1H-indazol-6-yl)sulfanyl]-N-methylbenzamide; 2-((1-Acetyl-3-iodo-1H-indazol-6-yl)thio)-N-methylbenzamide; UNII-9K8F8S3A4F; 9K8F8S3A4F; SCHEMBL21842227; AKOS040757623; A1-00319
EINECS	Contact for details

Quality Control

Our production of Benzamide, 2-[(1-Acetyl-3-Iodo-1H-Indazol-6-Yl)Thio]-n-Methyl- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.