Description

Methyl 3-(Trifluoromethyl)Thiophene-2-Carboxylate CAS NO 1638885-32-1 is a high-value fluorinated heterocyclic building block, specifically a thiophene derivative, essential for advanced organic synthesis. Its core value lies in the unique reactivity imparted by the trifluoromethyl group and the thiophene ring, enabling the construction of complex molecules with enhanced properties. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by material scientists developing specialty polymers and electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas requiring fluorinated motifs for improved metabolic stability, bioavailability, and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl-thiophene scaffold can contribute to enhanced biological activity and environmental profile.
• Material Science Precursor: Serves as a monomer or building block for conjugated polymers and organic semiconductors used in OLEDs, organic photovoltaics, and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis, leveraging the electron-withdrawing nature of the trifluoromethyl group to tune metal complex properties.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in fluoroorganic chemistry and heterocyclic compound synthesis.
• Liquid Crystal and Dye Intermediate: Used in the synthesis of fluorinated components for advanced display technologies and specialty dyes with unique optical properties.

Basic Information

Product Name	Methyl 3-(Trifluoromethyl)Thiophene-2-Carboxylate
CAS No.	1638885-32-1
Molecular Formula	C7H5F3O2S
Molecular Weight	210.17 g/mol
Synonyms	Methyl 3-(trifluoromethyl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-(trifluoromethyl)-, methyl ester; Methyl 3-trifluoromethylthiophene-2-carboxylate; 3-(Trifluoromethyl)thiophene-2-carboxylic acid methyl ester; Methyl 3-(trifluoromethyl)-2-thiophenecarboxylate; 2-Methoxycarbonyl-3-trifluoromethylthiophene
EINECS	Contact for details

Quality Control

Our Methyl 3-(Trifluoromethyl)Thiophene-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.