Description

Methyl 4-Bromo-2-Oxo-2,3-Dihydro-1H-Indole-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a defined bromo-substituted oxindole core structure. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting protein kinases and other enzymatic pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to construct more complex heterocyclic compounds and fused ring systems.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) settings for exploratory chemical synthesis and methodological studies.

Basic Information

Product Name	Methyl 4-Bromo-2-Oxo-2,3-Dihydro-1H-Indole-6-Carboxylate
CAS No.	1638768-53-2
Molecular Formula	C10H8BrNO3
Molecular Weight	270.08 g/mol
Synonyms	Methyl 4-bromo-2-oxo-2,3-dihydro-1H-indole-6-carboxylate; 4-Bromo-6-(methoxycarbonyl)-2,3-dihydro-1H-indol-2-one; 6-(Methoxycarbonyl)-4-bromo-2,3-dihydro-1H-indol-2-one; 4-Bromo-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester; 1H-Indole-6-carboxylic acid, 4-bromo-2,3-dihydro-2-oxo-, methyl ester; Methyl 4-bromo-2-oxindole-6-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-2-Oxo-2,3-Dihydro-1H-Indole-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with the standards required for pharmaceutical R&D and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.