Description

4-Bromoisoquinoline-6-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a brominated isoquinoline scaffold with a carboxylic acid functional group, enabling precise derivatization for complex molecule construction. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoquinoline core.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Functional Material Development: Incorporated into organic frameworks, polymers, or dyes to impart specific electronic or photophysical properties.
• Chemical Biology Probes: Utilized to build molecular tools for studying biological processes and target engagement.
• Academic & Contract Research: Essential for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Item	Details
Product Name	4-Bromoisoquinoline-6-Carboxylic Acid
CAS No.	1637280-23-9
Molecular Formula	C₁₀H₆BrNO₂
Molecular Weight	252.07 g/mol
Synonyms	6-Carboxy-4-bromoisoquinoline; 4-Bromo-6-isoquinolinecarboxylic Acid; 4-Bromo-6-carboxyisoquinoline; 4-Bromoisoquinoline-6-carboxylic acid; 1637280-23-9; AI3-63520; AKOS040759583; BRN 1252205; CS-W009767; FT-0770087; SCHEMBL21824027; ZINC000257841509
EINECS	Contact for details

Quality Control

Every batch of 4-Bromoisoquinoline-6-Carboxylic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.