Description

(1H-Indazol-4-Yl)Methanamine Dihydrochloride is a high-purity organic building block and pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, particularly those targeting kinase inhibition and other enzymatic pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a starting material or reference standard in the development of biochemical probes and assay reagents.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to introduce the (1H-indazol-4-yl)methanamine moiety into target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	(1H-Indazol-4-Yl)Methanamine Dihydrochloride
CAS No.	1630907-20-8
Molecular Formula	C8H12Cl2N3
Molecular Weight	221.11 g/mol
Synonyms	4-(Aminomethyl)-1H-indazole dihydrochloride; 1H-Indazole-4-methanamine dihydrochloride; (1H-Indazol-4-yl)methanamine hydrochloride (1:2); 4-(Aminomethyl)indazole dihydrochloride; 4-(Aminomethyl)-1H-indazole hydrochloride; 1630907-20-8
EINECS	Contact for details

Quality Control

Our (1H-Indazol-4-Yl)Methanamine Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We adhere to cGMP guidelines where applicable. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.