Description

Methyl 1-(Benzenesulfonyl)-6-Chloro-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct complex nitrogen-containing heterocycles of pharmaceutical interest.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying novel chemical reactions and developing new synthetic methodologies.

Basic Information

Item	Details
Product Name	Methyl 1-(Benzenesulfonyl)-6-Chloro-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate
CAS No.	1630907-18-4
Molecular Formula	C15H11ClN2O4S
Molecular Weight	350.78 g/mol
Synonyms	1-(Phenylsulfonyl)-6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; Methyl 6-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 6-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 6-chloro-1-(phenylsulfonyl)-, methyl ester; Methyl 1-(benzenesulfonyl)-6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 1630907-18-4; Benzenesulfonyl pyrrolopyridine carboxylate derivative
EINECS	Contact for details

Quality Control

Our Methyl 1-(Benzenesulfonyl)-6-Chloro-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.