Description

2-Azabicyclo[4.1.0]heptane-1-carboxylic acid, hydrochloride (1:1) is a high-purity, advanced pharmaceutical intermediate featuring a strained bicyclic structure. This compound matters as a critical building block for the synthesis of novel, complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral therapeutics. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and the production of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its constrained, three-dimensional scaffold.
• Process Chemistry: Serves as a starting material or intermediate in the scalable synthesis of complex molecules under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Employed in synthetic organic chemistry for studying cyclopropane-fused nitrogen heterocycles and ring-strain reactivity.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or bioconjugates for biochemical and diagnostic applications.

Basic Information

Product Name	2-Azabicyclo[4.1.0]heptane-1-Carboxylic Acid, Hydrochloride (1:1)
CAS No.	1628734-73-5
Molecular Formula	C7H11NO2 • HCl
Molecular Weight	177.63 g/mol
Synonyms	1-Azabicyclo[4.1.0]heptane-1-carboxylic acid, hydrochloride; 2-Azabicyclo[4.1.0]heptane-1-carboxylic acid HCl; (1R,6S)-2-Azabicyclo[4.1.0]heptane-1-carboxylic acid hydrochloride; Cyclopropa[c]piperidine-1-carboxylic acid, hydrochloride; 1-Carboxy-2-azabicyclo[4.1.0]heptane hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[4.1.0]heptane-1-carboxylic acid, hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.