Description

6-Methoxy-1,2,3,4-Tetrahydroisoquinolin-5-Ol Hcl is a high-purity organic compound belonging to the tetrahydroisoquinoline class, a privileged scaffold in medicinal chemistry. This compound serves as a critical building block (advanced pharmaceutical intermediate) for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex molecules for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Alkaloid Synthesis: Serves as a starting material or intermediate in the synthetic pathways of complex natural product analogs and alkaloids.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and receptor interactions.
• Library Synthesis for High-Throughput Screening: Used to generate focused compound libraries for biological screening against various disease targets.

Basic Information

Product Name	6-Methoxy-1,2,3,4-Tetrahydroisoquinolin-5-Ol Hydrochloride
CAS No.	1628638-77-6
Molecular Formula	C₁₀H₁₄ClNO₂
Molecular Weight	215.68 g/mol
Synonyms	6-Methoxy-1,2,3,4-tetrahydro-5-isoquinolinol hydrochloride; 5-Hydroxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 6-Methoxy-5-hydroxy-1,2,3,4-tetrahydroisoquinoline HCl; 6-Methoxy-1,2,3,4-tetrahydroisoquinolin-5-ol hydrochloride; 1628638-77-6; 6-MeO-THIQ-5-ol HCl
EINECS	Contact for details

Quality Control

Our 6-Methoxy-1,2,3,4-Tetrahydroisoquinolin-5-Ol Hcl is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.