Description

Isoquinolin-3-Ylmethanamine Hydrochloride CAS NO 1628557-04-9 is a high-purity organic salt derivative of isoquinoline, valued for its role as a versatile chemical building block and pharmaceutical intermediate. This compound is essential for research and development in medicinal chemistry, enabling the synthesis of novel compounds with potential therapeutic applications. It is primarily targeted at pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Ligand and Receptor Studies: Serves as a building block for creating specialized ligands used in biochemical assays and target validation.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the isoquinolin-3-ylmethanamine moiety into more complex molecular architectures.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and new synthetic methodology development.

Basic Information

Product Name	Isoquinolin-3-Ylmethanamine Hydrochloride
CAS No.	1628557-04-9
Molecular Formula	C₁₀H₁₀N₂·HCl
Molecular Weight	194.66 g/mol (Free base: 158.20 g/mol)
Synonyms	3-(Aminomethyl)isoquinoline hydrochloride; (Isoquinolin-3-yl)methanamine hydrochloride; 1-Isoquinolinemethanamine, 3-methyl-, hydrochloride; 3-Aminomethylisoquinoline HCl; Isoquinoline-3-methanamine hydrochloride; 3-(Aminomethyl)isoquinoline HCl salt; (3-Isoquinolyl)methylamine hydrochloride
EINECS	Contact for details

Quality Control

Our Isoquinolin-3-Ylmethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.