Description

4-Chloro-6-(2,2,2-trifluoroethyl)-thieno[2,3-d]pyrimidine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique molecular scaffold, combining a pyrimidine core with a thiophene ring and trifluoroethyl/chloro substituents, provides a versatile platform for creating novel bioactive molecules. Pharmaceutical and agrochemical R&D teams need it as a critical intermediate for developing new active ingredients, particularly in kinase inhibitor and antiviral research programs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for targeted therapies.
• Kinase Inhibitor Scaffold: Serves as a privileged core structure for designing and synthesizing potential kinase inhibitors.
• Agrochemical Synthesis: Used in the development of new generation herbicides and fungicides with enhanced activity.
• Material Science Research: Investigated as a building block for organic electronic materials due to its electron-deficient heterocyclic system.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis projects.

Basic Information

Product Name	4-Chloro-6-(2,2,2-trifluoroethyl)-thieno[2,3-d]pyrimidine
CAS No.	1628317-85-0
Molecular Formula	C8H4ClF3N2S
Molecular Weight	252.64 g/mol
Synonyms	4-Chloro-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine, 4-chloro-6-(2,2,2-trifluoroethyl)-; 6-(2,2,2-Trifluoroethyl)-4-chlorothieno[2,3-d]pyrimidine; 4-Chloro-6-(trifluoroethyl)thieno[2,3-d]pyrimidine; CAS 1628317-85-0
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(2,2,2-trifluoroethyl)-thieno[2,3-d]pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.