Description

6-Bromo-2-((R)-1-(4-Methoxyphenyl)Ethyl)-3-Methylisoindolin-1-One is a high-purity, chiral isoindolinone derivative with a bromine substituent, serving as a critical synthetic intermediate. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules in advanced pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications such as medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) or oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its chiral center and bromine handle for further functionalization.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Development: Intermediate in the research and synthesis of novel pesticides or herbicides.
• Fine Chemical Synthesis: Precursor for specialized dyes, pigments, or advanced materials requiring specific molecular architectures.
• Academic Research: Used in university and institutional labs for methodological development in organic and organometallic chemistry.

Basic Information

Product Name	6-Bromo-2-((R)-1-(4-Methoxyphenyl)Ethyl)-3-Methylisoindolin-1-One
CAS No.	1627696-46-1
Molecular Formula	C18H18BrNO2
Molecular Weight	360.25 g/mol
Synonyms	6-Bromo-2-[(1R)-1-(4-methoxyphenyl)ethyl]-3-methyl-1H-isoindol-1-one; (R)-6-Bromo-2-(1-(4-methoxyphenyl)ethyl)-3-methylisoindolin-1-one; 6-Bromo-2-[(R)-1-(4-methoxyphenyl)ethyl]-3-methylisoindolin-1-one; 1H-Isoindol-1-one, 6-bromo-2-[(1R)-1-(4-methoxyphenyl)ethyl]-3-methyl-; CAS 1627696-46-1; Bromo Isoindolinone Derivative; Chiral Bromo Isoindolinone
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-((R)-1-(4-Methoxyphenyl)Ethyl)-3-Methylisoindolin-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥95% by HPLC), and impurity profile is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.