Description

Bicyclo[2.2.2]Octane-2-Carboxylicacid,3-Amino-,Ethylester,Hydrochloride CAS NO 1626394-44-2 is a high-purity, functionalized bicyclic organic compound that serves as a critical chiral building block and intermediate in advanced chemical synthesis. Its rigid, three-dimensional bicyclo[2.2.2]octane scaffold and amino acid ester functionality make it invaluable for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for applications in medicinal chemistry, asymmetric catalysis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalysis: Used as a precursor for designing novel chiral ligands and organocatalysts, enabling stereoselective synthetic transformations.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Employed in the synthesis of specialty polymers, dendrimers, and advanced organic materials that require rigid, three-dimensional molecular components.
• Peptidomimetics & Bioactive Molecule Design: The amino acid ester moiety facilitates its incorporation into peptide analogs and other bioactive compounds to modulate stability and bioavailability.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	Bicyclo[2.2.2]Octane-2-Carboxylicacid,3-Amino-,Ethylester,Hydrochloride
CAS No.	1626394-44-2
Molecular Formula	C11H20ClNO2
Molecular Weight	233.73 g/mol
Synonyms	Ethyl 3-Aminobicyclo[2.2.2]octane-2-carboxylate hydrochloride; 3-Aminobicyclo[2.2.2]octane-2-carboxylic Acid Ethyl Ester Hydrochloride; Bicyclo[2.2.2]octan-2-carboxylic acid, 3-amino-, ethyl ester, hydrochloride; 2-Carboxybicyclo[2.2.2]octane-3-amino ethyl ester HCl; ABOC-OEt•HCl; (1R,2S,3S,4S)-3-Amino-2-ethoxycarbonylbicyclo[2.2.2]octane hydrochloride (stereoisomer)
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octane-2-Carboxylicacid,3-Amino-,Ethylester,Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.