Description

Ethyl 2-(2-(Dimethylamino)Pyrimidin-4-Yl)-1H-Indole-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop novel small-molecule therapeutics.
• Oncology Drug Development: A key scaffold for creating potential kinase inhibitors and other targeted cancer therapies due to its indole-pyrimidine core.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug development pipelines.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and new synthetic methodologies.
• Bioconjugation & Probe Synthesis: Potential use in creating chemical probes for biochemical and cellular assays.

Basic Information

Product Name	Ethyl 2-(2-(Dimethylamino)Pyrimidin-4-Yl)-1H-Indole-5-Carboxylate
CAS No.	1624260-37-2
Molecular Formula	C₁₇H₁₈N₄O₂
Molecular Weight	310.35 g/mol
Synonyms	Ethyl 2-[2-(dimethylamino)pyrimidin-4-yl]-1H-indole-5-carboxylate; 5-Carbethoxy-2-[2-(dimethylamino)-4-pyrimidinyl]indole; 1H-Indole-5-carboxylic acid, 2-[2-(dimethylamino)-4-pyrimidinyl]-, ethyl ester; 1624260-37-2; Ethyl 2-(2-(dimethylamino)pyrimidin-4-yl)indole-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(2-(Dimethylamino)Pyrimidin-4-Yl)-1H-Indole-5-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.