Description

7,7-Difluorotetrahydropyrrolo[1,2-A]Pyrazine-1,3(2H,4H)-Dione is a high-value, fluorinated heterocyclic building block of significant interest in modern synthetic chemistry. Its core value lies in its unique bicyclic structure containing both difluoromethylene and imide functionalities, which are critical for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies, where the fluorine atoms can enhance bioavailability and binding affinity.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the fluorine substitution to improve environmental stability and pesticidal activity.
• Material Science Precursor: Serves as a specialized monomer or additive in the research of high-performance polymers, coatings, and electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	7,7-Difluorotetrahydropyrrolo[1,2-A]Pyrazine-1,3(2H,4H)-Dione
CAS No.	1624260-16-7
Molecular Formula	C7H6F2N2O2
Molecular Weight	188.13 g/mol
Synonyms	7,7-Difluoro-2,3,4,6-tetrahydropyrrolo[1,2-a]pyrazine-1,3-dione; 7,7-Difluoro-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-1,3-dione; 7,7-Difluoro-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-1,3(2H)-dione; 1624260-16-7; 7,7-Difluorotetrahydropyrrolo[1,2-a]pyrazine-1,3-dione
EINECS	Contact for details

Quality Control

Our 7,7-Difluorotetrahydropyrrolo[1,2-A]Pyrazine-1,3(2H,4H)-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.