Description

Pyridine, 5-(Methyl-D3)-2-Phenyl- is a deuterium-labeled derivative of 2-phenyl-5-methylpyridine, a valuable building block in synthetic organic chemistry. This compound is specifically designed for use as an internal standard or a labeled precursor in advanced research and development, enabling precise quantification and metabolic pathway tracing. It is primarily utilized by pharmaceutical, agrochemical, and analytical laboratories engaged in drug discovery, environmental analysis, and material science research.

Application

• Pharmaceutical Research & Development: Serves as a deuterated internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate bioanalysis and pharmacokinetic study of related active pharmaceutical ingredients (APIs).
• Metabolic Pathway Tracing: Used as a stable isotope-labeled precursor to synthesize deuterated drug candidates, facilitating the study of drug metabolism and disposition in biological systems.
• Agrochemical Development: Acts as a key intermediate in the synthesis of novel, labeled agrochemicals for research into their environmental fate and residue analysis.
• Material Science: Employed in the development of advanced organic electronic materials and metal-organic frameworks (MOFs), where the deuterium label can be used to study molecular interactions and dynamics.
• Analytical Chemistry: Provides a critical reference standard for method development and validation in regulatory testing and quality control laboratories.

Basic Information

Product Name	Pyridine, 5-(Methyl-D3)-2-Phenyl-
CAS No.	1622235-49-7
Molecular Formula	C12H8D3N
Molecular Weight	172.23 g/mol
Synonyms	2-Phenyl-5-(trideuteriomethyl)pyridine; 5-(Methyl-d3)-2-phenylpyridine; 2-(5-(Methyl-d3)pyridinyl)benzene; Deuteronated 2-Phenyl-5-methylpyridine; [D3]-2-Phenyl-5-methylpyridine; 2-Phenyl-5-(CD3)pyridine; 5-(Trideuteromethyl)-2-phenylpyridine; Labeled Phenyl Methyl Pyridine Derivative
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 5-(Methyl-D3)-2-Phenyl- is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, supported by comprehensive analytical data including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and impurity profiles are provided with each shipment to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.