Description

Ulipristal Acetate-D6 is a deuterated analog of the selective progesterone receptor modulator (SPRM), Ulipristal Acetate, specifically labeled with six deuterium atoms. This stable isotope-labeled compound is an essential reference standard and internal standard for the precise quantification and pharmacokinetic studies of its parent drug in complex biological matrices. It is primarily required by pharmaceutical research and development laboratories, contract research organizations (CROs), and analytical testing facilities engaged in advanced LC-MS/MS method development, drug metabolism studies, and ensuring regulatory compliance for bioanalytical assays.

Application

• Primary use as a stable isotope-labeled internal standard for the accurate quantification of Ulipristal Acetate in bioanalytical methods using LC-MS/MS.
• Critical component in pharmacokinetic (PK) and drug metabolism studies to track absorption, distribution, metabolism, and excretion (ADME) profiles.
• Essential reference material for method validation and ensuring data integrity in regulatory submissions to agencies like the FDA and EMA.
• Used in clinical research for monitoring drug levels in patient samples during therapeutic studies.
• Supports forensic and anti-doping analysis where precise identification and quantification of the parent compound are required.
• Facilitates impurity profiling and characterization of pharmaceutical products containing Ulipristal Acetate.

Basic Information

Product Name	Ulipristal Acetate-D6
CAS No.	1621894-64-1
Molecular Formula	C30H31D6NO4
Molecular Weight	~ 485.64 g/mol
Synonyms	Ulipristal Acetate-d6; (17α)-17-Hydroxy-11β-[4-(methyl-d3)phenyl]-19-norpregna-4,9-diene-3,20-dione Acetate-3,3,20,20-d4; CDB-4124-d6; PGL4001-d6; Esmya-d6 (deuterated); Ella-d6 (deuterated); Selective Progesterone Receptor Modulator-d6; 11β-[4-(Methyl-d3)phenyl]-17α-acetoxy-19-nor-17α-pregna-4,9-diene-3,20-dione-3,3,20,20-d4
EINECS	Contact for details

Quality Control

Our Ulipristal Acetate-D6 is manufactured under controlled conditions to ensure the highest isotopic and chemical purity suitable for sensitive analytical applications. Each batch undergoes rigorous quality testing, including NMR and mass spectrometry for isotopic enrichment verification and HPLC for chemical purity assessment. Certificates of Analysis (COA) are provided, detailing batch-specific results for identity, purity (HPLC), isotopic purity, and residual solvents, ensuring compliance with internal specifications for reference standard materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, ideally between 15-25°C (59-77°F). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (by HPLC)	≥ 95.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.