Description

5-Bromo-2-(5-Chloroindolin-2-Yl)-3-Fluorophenol is a high-purity, multi-functional halogenated indole derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and research chemical for developing novel bioactive molecules. It is primarily utilized by R&D teams and process chemists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate complex halogenated phenolic motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated phenolic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular scaffold in probe discovery.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting cutting-edge organic synthesis and heterocyclic chemistry research.

Basic Information

Product Name	5-Bromo-2-(5-Chloroindolin-2-Yl)-3-Fluorophenol
CAS No.	1620450-59-0
Molecular Formula	C14H10BrClFNO
Molecular Weight	354.59 g/mol
Synonyms	5-Bromo-2-(5-chloro-2,3-dihydro-1H-indol-2-yl)-3-fluorophenol; 3-Fluoro-5-bromo-2-(5-chloroindolin-2-yl)phenol; 2-(5-Bromo-3-fluoro-2-hydroxyphenyl)-5-chloroindoline; (5-Chloroindolin-2-yl)(5-bromo-3-fluoro-2-hydroxyphenyl)methane; 1620450-59-0; 5-Bromo-2-(5-chloroindolin-2-yl)-3-fluorophenol
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(5-Chloroindolin-2-Yl)-3-Fluorophenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.