Description

5,8-Dichloro-3,4-Dihydroisoquinolin-1(2H)-One is a high-purity, synthetically valuable heterocyclic building block. This compound serves as a critical intermediate in advanced organic synthesis, enabling the development of novel pharmacologically active molecules. It is primarily required by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of complex isoquinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Agrochemical Development: Serves as a building block for creating novel active ingredients in crop protection research.
• Organic Synthesis: Employed in academic and industrial labs for constructing complex heterocyclic compounds and natural product analogs.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	5,8-Dichloro-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	1616289-34-9
Molecular Formula	C9H5Cl2NO
Molecular Weight	214.05 g/mol
Synonyms	5,8-Dichloro-1,2,3,4-tetrahydroisoquinolin-1-one; 5,8-Dichloro-3,4-dihydro-1(2H)-isoquinolinone; 5,8-Dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline; 1(2H)-Isoquinolinone, 5,8-dichloro-3,4-dihydro-; 5,8-Dichloro-1,2,3,4-tetrahydroisoquinoline-1-one
EINECS	Contact for details

Quality Control

Our 5,8-Dichloro-3,4-Dihydroisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your research and development documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.