Description

Methyl 8-Chloro-1-Oxo-7-(Propan-2-Yloxy)-1,2,3,4-Tetrahydroisoquinoline-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1616288-55-1. This compound is a key synthetic building block valued for its complex heterocyclic structure, which is integral to the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the synthesis of new therapeutic agents, particularly in areas requiring sophisticated isoquinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in research and development for constructing complex heterocyclic molecules in medicinal chemistry programs.
• Agrochemical Research: Serves as a starting material or intermediate in the development of new agrochemicals with specific biological activities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.
• Academic Research: Utilized in university and institutional labs for methodological studies and the exploration of new chemical reactions involving functionalized isoquinolines.

Basic Information

Product Name	Methyl 8-Chloro-1-Oxo-7-(Propan-2-Yloxy)-1,2,3,4-Tetrahydroisoquinoline-5-Carboxylate
CAS No.	1616288-55-1
Molecular Formula	C14H16ClNO4
Molecular Weight	297.73 g/mol
Synonyms	Methyl 8-chloro-7-isopropoxy-1-oxo-1,2,3,4-tetrahydroisoquinoline-5-carboxylate; 8-Chloro-7-isopropoxy-1-oxo-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid methyl ester; 5-Carbomethoxy-8-chloro-7-isopropoxy-3,4-dihydroisoquinolin-1(2H)-one; 1616288-55-1; 8-Chloro-7-(1-methylethoxy)-1-oxo-1,2,3,4-tetrahydro-5-isoquinolinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 8-Chloro-1-Oxo-7-(Propan-2-Yloxy)-1,2,3,4-Tetrahydroisoquinoline-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.